Global FAQ
Nerivio is intended for acute and/or preventive treatment of migraine in patients 12 years or older. It is a self-administered, prescription-use device for use at home either at the onset of a migraine for acute treatment or every other day for preventive treatment. It should not be used by people with uncontrolled epilepsy, active implantable devices, or proximity to cancerous lesions.
Nerivio can be used at any time, but it is most effective when used early, within 60 minutes of migraine onset. It can also be used for additional treatments if the headache is not relieved or if it reoccurs.
Nerivio can be used on either arm, regardless of the side of the headache.
You can order a new Nerivio or refill your device by contacting Nerivio support in your region. Find contact information here.
Nerivio is used for both acute and preventative treatments: Acute Treatment: At the onset of a migraine, 45-minute treatment. Preventative Treatment: Every other day, 45-minute treatment. Combining both: Use Nerivio every other day for prevention and as needed for acute treatment. If a migraine attack happens on a non-preventative treatment day, perform acute treatment.
Enable Bluetooth on your smartphone. For Android users, allow location access and services. To connect, turn on the device and press ‘Connect Nerivio’ in the app. Keep the device close to your smartphone during the first connection. After pairing, automatic connection happens when the device is turned on and the app is opened.
Nerivio will automatically turn off after: - 10 minutes after the first connection.- 3 minutes if treatment does not start.- 5 minutes after pausing the treatment.- 1 minute after the treatment ends. These timers do not affect the ability to provide 18 treatments.
The armband is designed to secure the device on your arm and ensure proper contact between the device and your skin for optimal treatment. During your first use, adjust the armband to fit your arm comfortably. The armband is available in 4 sizes (S, M, L, XL), and you can use the extension for L and XL sizes. If the smallest size is too loose, or if the largest size is too tight, please contact Nerivio Cares at 1-866-637-4846 for additional assistance or to request a different size.
You will feel electrical pulses. Start with a strong, but comfortable intensity. Sensations may include warmth, tingling, numbness, or redness, which should disappear after treatment. If uncomfortable, decrease the intensity. If you experience muscle twitching or hand numbness, move the device to a different location.
Yes, treatments do not require an internet connection. Internet is needed for app sign-up or sign-in, but once logged in, no internet is required for subsequent treatments.
Ensure the protective film is removed from refill unit, the device is connected to the app, and treatment has started. Increase the intensity if needed. If still no sensation, rub water on the electrodes of the refill unit to improve adhesion. Replace the device if the refill unit surface is damaged.
Nerivio can be used for 18 treatments (45 minutes each). After 18 treatments, dispose of the device according to instructions. You can contact Nerivio support for recycling details here. Store unused devices in the original packaging, and rub electrodes with water every four treatments to maintain adhesiveness.
Yes, you can connect multiple Nerivio devices to the same account. Each device can be paired with only one user at a time. You can use different devices at home, work, or carry one with you.
Adjust the intensity so it’s strong yet comfortable. Start low and increase to a point of discomfort, then reduce by 1-2%. In clinical trials, intensities below 20% were less effective. If the sensation feels weak during treatment, increase the intensity slightly.
Your privacy is very important to us, and your personal information is stored securely. Anonymous data may be used for scientific publications, reports and marketing. Your personal information, however, will never be shared without your consent. You can share your information with your healthcare provider and loved ones by exporting your diary and sending it via email or social apps.
No, Nerivio does not contain latex.
The manual can be downloaded and printed from the official site. It includes the English version and is applicable for the latest iOS and Android app versions. A quick start guide and video instructions are also available.
The Nerivio app requires:
- At least 4.7 inches multi-touchscreen with at least 720 x 1280 pixels resolution
- CPU of 1GHz or faster, internal memory of 4GB or more, and internal storage of at least 64GB
- Connectivity capabilities of BT4.0 or above
- Supported operating systems - iOS versions 16 or newer and Android versions 17 or newer
- NFC connectivity capabilities when using Nerivio Infinity.
Yes. Nerivio provides several tools, all found in the Log and Track tabs, to help you track your migraine disease and treatment.
The Log tab lets you record your headaches, associated symptoms, prodromal symptoms, and treatments on a daily basis. It's recommended to log every day, including on non-migraine days, to get the full benefit of these tools.
The Track tab builds on your logged data with three features:
1. Preventive Treatment Consistency shows how closely you're following your every-other-day preventive treatment plan, including a weekly status (Not Started, Getting There, On Course), Personal Milestone badges for consecutive On Course weeks, and a Community Standing ranking. Available for preventive or dual-use patients. Can be turned off in Settings.
2. Migraine Patterns summarizes your headache days and treatments over time across different timeframes and provides personal data insights.
3. Your Day Ahead provides an outlook on your likelihood of experiencing a migraine attack in the next 24 hours, based on your logged data processed by a machine learning algorithm. This is not a clinical diagnosis — it is a wellness feature providing personal insight to help you plan your day. To see your outlook, complete at least one pre-treatment questionnaire or a diary entry; your likelihood will show as Very Low, Low, Moderate, or High. Can be turned off in Settings.
You can export your data and share it with your healthcare provider or loved ones using the Share icon in the Track tab.
The GIER Up! button activates Guided Imagery, Education, and Relaxation (GIER) behavioral therapy, which enhances migraine relief during treatments.
GIER is Guided Imagery, Education, and Relaxation therapy. Access it by pressing the “GIER Up!” button during a treatment session in the app.
Clinical studies show that 66.7% of users experience pain relief, and 37.4% achieve pain freedom 2 hours post-treatment. Preventive treatments show a mean reduction of 4 migraine days per month after two months. For detailed clinical studies, visit here.
Nerivio is not a TENS unit. It uses remote electrical neurostimulation (REN) to activate pain-relieving mechanisms in the brainstem, unlike TENS, which targets local nerves and requires application at the site of pain.