How To Use REN Wearable

Remote Electrical Neuromodulation, in short REN, is an innovative technology used for migraine treatment and prevention.

The Nerivio REN wearable is controlled by an app and worn on the upper arm for a 45-minute treatment. Starting a treatment session takes just a couple of clicks—simply connect, wear, set, and treat. During the session, you can continue your day uninterrupted, take a rest, or stay on the go.

REN Wearable Models

Nerivio® Infinity

Rechargeable REN Wearable • Rx Only
All new Nerivio prescriptions now come with the rechargeable Nerivio Infinity

Nerivio Infinity Starter Set

For the first order of the new prescription only
Nerivio Infinity Refill Unit
(18 treatments)
Plus, Free of Charge Starter Set:
1 Nerivio Infinity Rechargeable Device
1 Durable Adjustable Armband
1 USB-C Charger Cable
1 Travel Pouch
Retail Price
Up to $1,598
With Any Medical or
Pharmacy Insurance:
Co-insurance up to $89
(No more than $4.90 per treatment)

Nerivio Infinity Refill Unit

Nerivio Infinity Refill Unit
(18 treatments)
Retail Price
Up to $1,598
With Any Medical or
Pharmacy Insurance:
Co-insurance up to $89
(No more than $4.90 per treatment)

* ​​Nerivio Infinity is covered either by your insurance or through the Nerivio Savings Program for eligible patients.

How to Use Nerivio Infinity?

Connect

Connect the Nerivio Infinity device to the Nerivio app and scan the Nerivio Infinity Refill Unit via NFC to activate it.

Wear

Place the Nerivio Infinity Refill Unit on your upper arm, snap the Nerivio Infinity Device on top, and secure it with the armband.

Set

Increase the treatment intensity to be strong yet comfortable

Treat

Treat for 45-minutes, while continuing with your day

Watch These Videos to Help Get You Started

Nerivio®

Disposable REN Wearable • Rx Only
Legacy model sold only for refills of existing Nerivio Rxs

Nerivio - Refill Device

Nerivio Refill Device
(18 treatments)
* Order a new refill when you have 8 treatments left so you never run out.
Retail Price
Up to $1,598
With Any Medical or
Pharmacy Insurance:
Co-insurance up to $89
(No more than $4.90 per treatment)

Nerivio Infinity Refill Unit

Nerivio Infinity Refill Unit
(18 treatments)
Retail Price
Up to $1,598
With Any Medical or Pharmacy Insurance:
Co-insurance up to $89
(No more than $4.90 per treatment)

How to Use Nerivio?

Connect

Connect the Nerivio device to the app on your smartphone

Wear

Place Nerivio on your arm and secure it with the armband

Set

Increase the treatment intensity to be strong yet comfortable

Treat

Treat for 45-minutes, while continuing with your day

Watch These Videos to Help Get You Started

When To Use The Nerivio REN Wearable

Nerivio is a prescription therapy to be used as directed by your healthcare provider. It is indicated for acute treatment, migraine prevention treatment, or dual (acute and preventive) therapy.

Acute Treatment

How To Use
Use Nerivio as often as needed for 45 minutes to treat each migraine attack.

For Best Results
Start treatment as early as possible at the first sign of migraine (headache and/or aura).
Clinical data shows Nerivio is most effective when used within the first 60 minutes of symptom onset.

Track & Optimize
The Nerivio app allows you to log treatments and symptoms, helping you track patterns and optimize timing.

Key Takeaway
Treating early is essential — migraine relief begins with prompt action.

Preventive Treatment

How To Use
Use Nerivio every other day for 45 minutes to help prevent migraine attacks.

For Best Results

Full benefit is typically seen after 6–8 weeks of consistent use. Clinical data shows that patients who complete 25–30 treatments within the first 2 months are significantly more likely to experience long-term improvement.

Stay on Track
The Nerivio app includes reminders and tracking tools to support adherence and help you stay on track.

Key Takeaway
Preventive therapy builds gradually — consistency over time is key.

What Can You Do During Nerivio Treatment?

Nerivio is designed to integrate effortlessly into your life, allowing you carry on with your daily activities or rest during the treatment session—as your symptoms allow.

Here are some ways Nerivio users make the most of their treatment time:

Stay focused in class

Attend meetings at work

Tackle chores or run errands

Spend quality time with family and friends

Take time to rest and relax

Use the GIER feature for migraine tailored relaxation and exercises

What Will You Feel During Nerivio Treatment?

Nerivio is a non-invasive neurostimulation treatment. During a treatment, the Nerivio device transmits gentle electrical pulses that feel like a tingling sensation, often described as a mild vibration or pulsing. Treatment intensity should be adjusted through the app to ensure it feels strong but comfortable.